Returning from a year-long psychological leave of absence after surviving an almost-fatal gunshot wound to the head, Detective David Creegan is assigned to the FBI's Organized and Serial Crime Unit – a rapid-response, elite crime investigation squad – where he and his new partner, Detective Susan Branca, find themselves committed to saving lives and solving cases. In spite of his inability to abide by common sense and the laws he's sworn to uphold, Creegan, with the help of Branca, works on hunting down the most vicious criminals on the streets.

Jeffrey Donovanas Detective David Creegan
Brian Markinsonas Special Agent Charles Bernal
Vera Farmigaas Detective Susan Branca
Zach Grenieras Special Agent Hank Enright
Kevin Durandas Special Agent Jay Swopes
Bradley Cooperas OSC Agent Mark Rivers
Terry Lewisas Man in car
Callum Keith Rennieas Mike Espy
Bruno Heller