Follows the surreal adventures of a cow, named Cow, and her chicken brother, named Chicken. They are often antagonized by "The Red Guy", who poses as various characters to scam them.

Charlie Adleras Cow / Chicken / The Red Guy / I.R. Baboon (voice)
Candi Miloas Mom / Teacher (voice)
Dee Bradley Bakeras Dad (voice)
Michael Dornas I.M. Weasel (voice)
Stuart Pankinas Sergeant / Mailman / Duck Walla (voice)
Glenn Shadixas Poopy the Clown / Gate Guard / Prisoner (voice)
Robert Ridgelyas Dr. Chunks (voice)
Jess Harnellas French Prime Minister / Admiral Bullets / Workman (voice)
Gregg Bergeras Mr. Draftsman / Worker #1 / Workman (voice)
Gail Matthiusas Nurse / Woman #1 (voice)
David Feiss
Michael Ryan
Steve Marmel
Maxwell Atoms
Richard Pursel
Seth MacFarlane
Genndy Tartakovsky
Guy Moon