Wreck-It Ralph is the 9-foot-tall, 643-pound villain of an arcade video game named Fix-It Felix Jr., in which the game's titular hero fixes buildings that Ralph destroys. Wanting to prove he can be a good guy and not just a villain, Ralph escapes his game and lands in Hero's Duty, a first-person shooter where he helps the game's hero battle against alien invaders. He later enters Sugar Rush, a kart racing game set on tracks made of candies, cookies and other sweets. There, Ralph meets Vanellope von Schweetz who has learned that her game is faced with a dire threat that could affect the entire arcade, and one that Ralph may have inadvertently started.

John C. Reillyas Ralph (voice)
Sarah Silvermanas Vanellope (voice)
Jack McBrayeras Felix (voice)
Jane Lynchas Calhoun (voice)
Alan Tudykas King Candy (voice)
Rich Mooreas Sour Bill / Zangief (voice)
Raymond S. Persias Gene / Zombie (voice)
Mindy Kalingas Taffyta Muttonfudge (voice)
Jamie Elmanas Rancis Fluggerbutter (voice)
Adam Carollaas Wynnchel (voice)