A retired San Francisco detective suffering from acrophobia investigates the strange activities of an old friend's wife, all the while becoming dangerously obsessed with her.

James Stewartas Det. John 'Scottie' Ferguson
Kim Novakas Madeleine Elster / Judy Barton
Barbara Bel Geddesas Marjorie 'Midge' Wood
Tom Helmoreas Gavin Elster
Henry Jonesas Coroner
Raymond Baileyas Scottie's Doctor
Ellen Corbyas Manager of McKittrick Hotel
Konstantin Shayneas Pop Leibel
Lee Patrickas Car Owner Mistaken for Madeleine
Bess Flowersas Diner at Ernie's (uncredited)
Robert Burks