A submarine commander is on a relentless pursuit of a Japanese aircraft carrier in the South Seas during World War II.

Glenn Fordas Lt. Cmdr. Barney Doyle
Ernest Borgnineas Lt. Archer 'Archie' Sloan
Diane Brewsteras Jane Doyle
Dean Jonesas Lt. Jake 'Fuzz' Foley
L.Q. Jonesas 'Hash' Benson
Philip Oberas Adm. Samuel Setton
Richard Carlyleas Cmdr. Don Adams
Fredd Wayneas Orville 'Goldy' Goldstein
Don Keeferas Ens. Ron Milligan
Robert Hardyas Lt. Redley
George J. Folsey