When vengeful General Francis X. Hummel seizes control of Alcatraz Island and threatens to launch missiles loaded with deadly chemical weapons into San Francisco, only a young FBI chemical weapons expert and notorious Federal prisoner have the skills to penetrate the impregnable island fortress and take him down.

Sean Conneryas John Patrick Mason
Nicolas Cageas Dr. Stanley Goodspeed
Ed Harrisas Brigadier General Francis X. Hummel, USMC
John Spenceras FBI Director James Womack
David Morseas Major Tom Baxter
William Forsytheas Special Agent Ernest Paxton
Michael Biehnas Commander Charles Anderson
Vanessa Marcilas Carla Pestalozzi
John C. McGinleyas Marine Captain Hendrix
Gregory Sporlederas Captain Frye
John Schwartzman