When a US Naval captain shows signs of mental instability that jeopardize his ship, the first officer relieves him of command and faces court martial for mutiny.

Humphrey Bogartas Lt. Cmdr. Philip Francis Queeg
Robert Francisas Ens. Willis Seward 'Willie' Keith
Van Johnsonas Lt. Stephen Maryk
Fred MacMurrayas Lt. Thomas 'Tom' Keefer
May Wynnas May Wynn
Katherine Warrenas Mrs. Keith
Jerry Parisas Ens. Barney Harding
José Ferreras Lt. Barney Greenwald
E.G. Marshallas Lt. Comdr. Challee
Tom Tullyas Comdr. DeVriess