The tragic story of French naïve painter Séraphine Louis aka Séraphine de Senlis (1864-1942), a humble servant who becomes a gifted self-taught painter. Discovered by prominent critic and collector William Uhde, she came to prominence between the wars grouped with other naïve painters like Henri Rouseau only to descend into madness and obscurity with the onset of the Great Depression and World War II.

Yolande Moreauas Séraphine Louis, dite Séraphine de Senlis
Ulrich Tukuras Wilhelm Uhde
Anne Bennentas Anne-Marie Uhde
Geneviève Mnichas Mme Duphot
Nico Rogneras Helmut Kolle
Adélaïde Lerouxas Minouche
Françoise Lebrunas La mère supérieure
Hélène Hardouinas La propriétaire
Serge Larivièreas Duval
Léna Brébanas Sœur Marguerite
Laurent Brunet