In Prohibition-era Chicago, musicians Joe and Jerry witness a mob hit, and flee the state in an all-female band disguised as Josephine and Daphne, but further complications set in.

Tony Curtisas Joe (Josephine)
Jack Lemmonas Jerry (Daphne)
Marilyn Monroeas Sugar Kane Kowalczyk
George Raftas Spats Colombo
Pat O'Brienas Detective Mulligan
Joe E. Brownas Osgood Fielding III
Nehemiah Persoffas Little Bonaparte
Joan Shawleeas Sweet Sue
George E. Stoneas Toothpick Charlie
Charles Lang