Paul, a former womanizer, marries the head of the medical department's "unattractive" daughter Christine because he thinks attractive women can't be trusted and make poor wives. A car accident leaves him bedridden and he begins to miss his playboy days, when Christine's bombshell sister Martine arrives and Paul decides he must have her. He begins drugging Christine at night so he can sneak out to kill of Martine's many suitors one by one.

Jean-Paul Belmondoas Le docteur Paul Simay
Mia Farrowas Christine Dupont
Laura Antonellias Martine Dupont
Marlène Appeltas L'Infirmière Carole
Dominique Zardias L'évêque
Daniel Lecourtoisas Le professeur Dupont
Daniel Ivernelas Le docteur Berthier
Patrick Préjeanas Arthur Ringard
Michel Peyrelonas Joseph Melville
Henri Attalas 'La sourde'