Lewis, a brilliant young inventor, is keen on creating a time machine to find his mother, who abandoned him in an orphanage. Things take a turn when he meets Wilbur Robinson and his family.

Daniel Hansenas Lewis (voice)
Jordan Fryas Lewis (voice)
Wesley Singermanas Wilbur (voice)
Matthew Jostenas Michael 'Goob' Yagoobian (voice)
Stephen J. Andersonas Bowler Hat Guy / Grandpa Bud / Tallulah (voice)
Tom Selleckas Cornelius Robinson (voice)
Tom Kennyas Mr. Willerstein (voice)
Laurie Metcalfas Lucille Krunklehorn (voice)
Angela Bassettas Mildred (voice)
Nicole Sullivanas Franny (voice)