Gru and Lucy and their girls—Margo, Edith and Agnes—welcome a new member to the Gru family, Gru Jr., who is intent on tormenting his dad. Gru also faces a new nemesis in Maxime Le Mal and his femme fatale girlfriend Valentina, forcing the family to go on the run.

Steve Carellas Gru (voice)
Kristen Wiigas Lucy (voice)
Will Ferrellas Maxime (voice)
Sofía Vergaraas Valentina (voice)
Miranda Cosgroveas Margo (voice)
Dana Gaier Ellisas Edith (voice)
Madison Skyy Polanas Agnes (voice)
Pierre Coffinas Minions (voice)
Chris Renaudas Principal Übelschlecht (voice)
Steve Cooganas Silas (voice)