Otis is a mischievous, carefree Holstein cow who lives on a farm where, unbeknownst to humans, the animals are anthropomorphic. He prefers having fun with his best friends: Pip the mouse, Freddy the ferret, Peck the rooster, and Pig the pig - rather than following strict rules and accepting responsibility. But when his adoptive father is killed in a coyote attack, he has a heavy responsibility thrust upon him to become leader of his farm home's community.

Kevin Jamesas Otis (voice)
Courteney Coxas Daisy (voice)
Sam Elliottas Ben (voice)
Danny Gloveras Miles (voice)
Wanda Sykesas Bessy (voice)
Andie MacDowellas Etta (voice)
David Koechneras Dag (voice)
Jeffrey Garciaas Pip (voice)
Cam Clarkeas Freddy (voice)
Rob Paulsenas Peck / Gopher / Pizza Twin #1 / Wild Mike (voice)