An intense look at the lives of the strong-willed daughters of the Weston family, whose paths have diverged until a family crisis brings them back to the Midwest house they grew up in, and to the dysfunctional mother who raised them.

Meryl Streepas Violet Weston
Julia Robertsas Barbara Weston
Julianne Nicholsonas Ivy Weston
Juliette Lewisas Karen Weston
Ewan McGregoras Bill Fordham
Margo Martindaleas Mattie Fae Aiken
Abigail Breslinas Jean Fordham
Chris Cooperas Charlie Aiken
Dermot Mulroneyas Steve Huberbrecht
Benedict Cumberbatchas Little Charles Aiken
Adriano Goldman