A large spider from the jungles of South America is accidentally transported in a crate with a dead body to America where it mates with a local spider. Soon after, the residents of a small California town disappear as the result of spider bites from the deadly spider offspring. It's up to a couple of doctors with the help of an insect exterminator to annihilate these eight legged freaks.

Jeff Danielsas Ross Jennings
Harley Jane Kozakas Molly Jennings
John Goodmanas Delbert McClintock
Julian Sandsas Dr. James Atherton
Brian McNamaraas Chris Collins
Stuart Pankinas Sheriff Parsons
Henry Jonesas Dr. Sam Metcalf
Peter Jasonas Henry Beechwood
Mark L. Tayloras Jerry Manley
James Handyas Milton Briggs
Mikael Salomon