When the beloved cellist of a world-renowned string quartet is diagnosed with a life threatening illness, the group's future suddenly hangs in the balance as suppressed emotions, competing egos and uncontrollable passions threaten to derail years of friendship and collaboration. As they are about to play their 25th anniversary concert — quite possibly their last — only their intimate bond and the power of music can preserve their legacy.

Christopher Walkenas Peter Mitchell
Philip Seymour Hoffmanas Robert Gelbart
Mark Ivaniras Daniel Lerner
Catherine Keeneras Juliette Gelbart
Imogen Pootsas Alexandra Gelbart
Liraz Charhias Pilar
Madhur Jaffreyas Dr. Nadir
Anne Sofie von Otteras Miriam Mitchell
Wallace Shawnas Gideon Rosen
Frederick Elmes