While planet Earth poises on the brink of nuclear self-destruction, a team of Russian and American scientists aboard the Leonov hurtles to a rendezvous with the still-orbiting Discovery spacecraft and its sole known survivor, the homicidal computer HAL.

Roy Scheideras Dr. Heywood Floyd
John Lithgowas Dr. Walter Curnow
Helen Mirrenas Tanya Kirbuk
Bob Balabanas Dr. R. Chandra
Keir Dulleaas Dr. David Bowman
Douglas Rainas HAL 9000 (voice)
Madolyn Smith Osborneas Caroline Floyd
Savely Kramarovas Dr. Vladimir Rudenko
Taliesin Jaffeas Christopher Floyd
James McEachinas Victor Milson
Peter Hyams